Older type 2 diabetic males do not exhibit abnormal pulmonary oxygen uptake and muscle oxygen utilization dynamics during submaximal cycling exercise.

Older type 2 diabetic males do not exhibit abnormal pulmonary oxygen uptake and muscle oxygen utilization dynamics during sub-maximal cycling exercise Running head: Oxygen uptake kinetics in older Type 2 diabetic patients

Skeletal muscle deoxygenation after the onset of moderate exercise suggests slowed microvascular blood flow kinetics in type 2 diabetes.

OBJECTIVE People with type 2 diabetes have impaired exercise responses even in the absence of cardiovascular complications. One key factor associated with the exercise intolerance is abnormally slowed oxygen uptake (VO2) kinetics during submaximal exercise. The mechanisms of this delayed adaptation during exercise are unclear but probably relate to impairments in skeletal muscle blood flow. Thi...

Skeletal Muscle Deoxygenation Following the Onset of Moderate Exercise Suggests Slowed Microvascular Blood Flow Kinetics in Type 2 Diabetes

Objective: People with type 2 diabetes (T2DM) have impaired exercise responses even in the absence of cardiovascular complications. One key factor associated with the exercise intolerance is abnormally slowed oxygen uptake ( O2) kinetics during submaximal exercise. The mechanisms of this delayed adaptation during exercise are unclear but likely relate to impairments in skeletal muscle blood flo...

Maximal strength training and increased work efficiency: contribution from the trained muscle bed.

Maximal strength training (MST) reduces pulmonary oxygen uptake (Vo(2)) at a given submaximal exercise work rate (i.e., efficiency). However, whether the increase in efficiency originates in the trained skeletal muscle, and therefore the impact of this adaptation on muscle blood flow and arterial-venous oxygen difference (a-vO(2diff)), is unknown. Thus five trained subjects partook in an 8-wk M...

Gender differences in substrate utilization during submaximal exercise in endurance-trained subjects.

Substrate utilization across the leg during 90 min of bicycle exercise at 58% of peak oxygen uptake (VO(2 peak)) was studied in seven endurance-trained males and seven endurance-trained, eumenorrheic females by applying arteriovenous catheterization, stable isotopes, and muscle biopsies. The female and male groups were matched according to VO(2 peak) per kilogram of lean body mass, physical act...